{"id":7977,"date":"2025-10-16T15:19:52","date_gmt":"2025-10-16T13:19:52","guid":{"rendered":"https:\/\/ed-pepper.eu\/?p=7977"},"modified":"2025-10-16T15:22:31","modified_gmt":"2025-10-16T13:22:31","slug":"september-25-newspepper","status":"publish","type":"post","link":"https:\/\/ed-pepper.eu\/en\/september-25-newspepper\/","title":{"rendered":"September 25 NewsPepper"},"content":{"rendered":"\n<p>\ud835\udde7\ud835\uddf5\ud835\uddf2 \ud835\udde6\ud835\uddf2\ud835\uddfd\ud835\ude01\ud835\uddf2\ud835\uddfa\ud835\uddef\ud835\uddf2\ud835\uddff 2025 \ud835\uddf2\ud835\uddf1\ud835\uddf6\ud835\ude01\ud835\uddf6\ud835\uddfc\ud835\uddfb \ud835\uddfc\ud835\uddf3 \ud835\udde1\ud835\uddf2\ud835\ude04\ud835\ude00\ud835\udde3\ud835\uddf2\ud835\uddfd\ud835\uddfd\ud835\uddf2\ud835\uddff \ud835\uddf6\ud835\ude00 \ud835\uddfb\ud835\uddfc\ud835\ude04 \ud835\uddf9\ud835\uddf6\ud835\ude03\ud835\uddf2!<br><br>Dive into the latest on endocrine disruption, regulation, method validation, and Pepper\u2019s journey bridging research and regulatory impact.<br><br>\ud83d\udd0d What\u2019s inside this issue:<br><br>\ud83d\udea8 Policy spotlights<br>\ud83d\udcc5 Events recap &amp; upcoming<br>\ud83e\uddea Pepper news: New validation report submitted to OECD, draft test guideline progress, &#8230;<br>\ud83d\udce3 NAMWISE update: New video interviews &amp; insights into the future of non-animal methods<br><br><br>\ud835\udde5\ud835\uddf2\ud835\uddee\ud835\uddf1 \ud835\ude01\ud835\uddf5\ud835\uddf2 \ud835\uddf3\ud835\ude02\ud835\uddf9\ud835\uddf9 \ud835\uddfb\ud835\uddf2\ud835\ude04\ud835\ude00\ud835\uddf9\ud835\uddf2\ud835\ude01\ud835\ude01\ud835\uddf2\ud835\uddff \ud835\uddf5\ud835\uddf2\ud835\uddff\ud835\uddf2: <a href=\"https:\/\/lnkd.in\/exjBFuQf\">https:\/\/lnkd.in\/exjBFuQf<\/a><br><br>Don\u2019t miss the next one, register NOW: <a href=\"https:\/\/lnkd.in\/eBDMhNWd\">https:\/\/lnkd.in\/eBDMhNWd<\/a><\/p>\n\n\n\n<!DOCTYPE html><html xmlns=\"http:\/\/www.w3.org\/1999\/xhtml\" 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{\nbody{background-image:url(\"https:\/\/dim.mcusercontent.com\/cs\/679c707fab1e7bd2bc8364edc\/images\/e9dc3c5c-885e-cae3-1b86-932b4a26350d.jpg?w=1800&dpr=2\");}\n}\n}<\/style><\/head>\n<body>\n<!---->\n<!--[if !gte mso 9]><!----><span class=\"mcnPreviewText\" style=\"display:none; font-size:0px; line-height:0px; max-height:0px; max-width:0px; opacity:0; overflow:hidden; visibility:hidden; mso-hide:all;\">September 2025<\/span><!--<![endif]-->\n<!---->\n<div style=\"display: none; max-height: 0px; overflow: hidden;\">\u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c \u00a0 \u2007  \u034f \u200c 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\u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad \u00ad<\/div><!--MCE_TRACKING_PIXEL-->\n<center>\n<table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" height=\"100%\" width=\"100%\" id=\"bodyTable\" style=\"background-color: rgb(0, 161, 216);\">\n<tbody><tr>\n<td class=\"bodyCell\" 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src=\"https:\/\/mcusercontent.com\/679c707fab1e7bd2bc8364edc\/images\/aa12c20d-74c9-007e-434d-2d69c393e7f4.jpg\" width=\"660\" height=\"auto\" style=\"display:block;max-width:100%;height:auto;border-radius:0\" class=\"imageDropZone mceImage\"><\/td><\/tr><\/tbody><\/table><\/a><div><!--<![endif]--><\/div><div>\n<!--[if mso]>\n<a href=\"https:\/\/ed-pepper.eu\"><span class=\"mceImageBorder\" style=\"border:0;border-width:2px;vertical-align:top;margin:0\"><img decoding=\"async\" role=\"presentation\" class=\"imageDropZone mceImage\" src=\"https:\/\/mcusercontent.com\/679c707fab1e7bd2bc8364edc\/images\/aa12c20d-74c9-007e-434d-2d69c393e7f4.jpg\" alt=\"\" width=\"660\" height=\"auto\" style=\"display:block;max-width:660px;width:660px;height:auto\"\/><\/span><\/a>\n<![endif]-->\n<\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><!--[if (gte mso 9)|(IE)]><\/td><\/tr><\/table><![endif]--><\/td><\/tr><\/tbody><tbody 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valign=\"top\" class=\"mceColumn\" id=\"mceColumnId-125\" data-block-id=\"125\" colspan=\"8\" width=\"66.66666666666666%\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0\" valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-122\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" id=\"b122\"><table width=\"100%\" style=\"border:0;background-color:transparent;border-radius:0;border-collapse:separate\"><tbody><tr><td style=\"padding-left:24px;padding-right:24px;padding-top:12px;padding-bottom:12px\" class=\"mceTextBlockContainer\"><div data-block-id=\"122\" class=\"mceText\" id=\"d122\" style=\"width:100%\"><h2><\/h2><h2 class=\"last-child\"><span style=\"font-size: 16px\">Welcome the 3rd\u00a0newsletter (NewsPepper) from Pepper in 2025. <br>We provide updates on our activities and general important issues in the world of Endocrine Disruption sciences. <br>Enjoy.<\/span><\/h2><\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><td style=\"padding-top:0;padding-bottom:0\" valign=\"top\" class=\"mceColumn\" id=\"mceColumnId-127\" data-block-id=\"127\" colspan=\"4\" width=\"33.33333333333333%\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0\" valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-87\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" id=\"b87\"><table width=\"100%\" style=\"border:0;background-color:#f5f7f9;border-radius:0;border-collapse:separate\"><tbody><tr><td style=\"padding-left:24px;padding-right:24px;padding-top:12px;padding-bottom:12px\" class=\"mceTextBlockContainer\"><div data-block-id=\"87\" class=\"mceText\" id=\"d87\" style=\"width:100%\"><p><strong><span style=\"color:#000000;\"><span style=\"font-size: 12px\">Summary<\/span><\/span><\/strong><\/p><p><span style=\"color:#000000;\"><span style=\"font-size: 12px\"> \u00a0 \u00a01. Policy News<\/span><\/span><\/p><p><span style=\"color:#000000;\"><span style=\"font-size: 12px\"> \u00a0 \u00a02. Past &amp; Upcoming Event<\/span><\/span><\/p><p><span style=\"color:#000000;\"><span style=\"font-size: 12px\"> \u00a0 \u00a03. Pepper\u2019s News<\/span><\/span><\/p><p><span style=\"color:#000000;\"><span style=\"font-size: 12px\"> \u00a0 \u00a0 \u00a0 \u00a0 <\/span><\/span><em><span style=\"color:#000000;\"><span style=\"font-size: 12px\"> Publication<\/span><\/span><\/em><\/p><p><em><span style=\"color:#000000;\"><span style=\"font-size: 12px\"> \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Test guidelines<\/span><\/span><\/em><\/p><p><em><span style=\"color:#000000;\"><span style=\"font-size: 12px\"> \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Member call<\/span><\/span><\/em><\/p><p class=\"last-child\"><span style=\"color:#000000;\"><span style=\"font-size: 12px\"> \u00a0 \u00a04. NAMWISE update<\/span><\/span><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-44\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:12px;padding-bottom:12px;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" class=\"mceLayoutContainer\" id=\"b44\"><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\" data-block-id=\"44\" id=\"section_f6373ccd93ed1a80497d89a7db1b8974\" class=\"mceLayout\"><tbody><tr class=\"mceRow\"><td style=\"background-position:center;background-repeat:no-repeat;background-size:cover\" valign=\"top\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td valign=\"top\" class=\"mceColumn\" id=\"mceColumnId--20\" data-block-id=\"-20\" colspan=\"12\" width=\"100%\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"border:0;border-radius:0\" valign=\"top\" align=\"center\" id=\"b-8\"><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\" data-block-id=\"-8\"><tbody><tr class=\"mceRow\"><td style=\"background-position:center;background-repeat:no-repeat;background-size:cover\" valign=\"top\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td valign=\"top\" class=\"mceColumn\" id=\"mceColumnId--25\" data-block-id=\"-25\" colspan=\"12\" width=\"100%\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"border:0;border-radius:0\" valign=\"top\" id=\"b49\"><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\" data-block-id=\"49\"><tbody><tr class=\"mceRow\"><td style=\"background-position:center;background-repeat:no-repeat;background-size:cover\" valign=\"top\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"24\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0\" valign=\"top\" class=\"mceColumn\" id=\"mceColumnId-46\" data-block-id=\"46\" colspan=\"12\" width=\"100%\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0\" valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-27\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" id=\"b27\"><table width=\"100%\" style=\"border:0;background-color:transparent;border-radius:0;border-collapse:separate\"><tbody><tr><td style=\"padding-left:24px;padding-right:24px;padding-top:12px;padding-bottom:12px\" class=\"mceTextBlockContainer\"><div data-block-id=\"27\" class=\"mceText\" id=\"d27\" style=\"width:100%\"><p><br><\/p><h1 class=\"last-child\">Policy News<\/h1><\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0\" valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-88\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" id=\"b88\"><table width=\"100%\" style=\"border:0;background-color:transparent;border-radius:0;border-collapse:separate\"><tbody><tr><td style=\"padding-left:24px;padding-right:24px;padding-top:12px;padding-bottom:12px\" class=\"mceTextBlockContainer\"><div data-block-id=\"88\" class=\"mceText\" id=\"d88\" style=\"width:100%\"><h4 style=\"text-align: left;\">Regulatory &amp; Policy Developments<\/h4><p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\"><strong> \u00a0 \u00a01. ECHA Released an Updated PFAS Restriction Proposal (late August 2025)<\/strong><\/p><p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\">The European Chemicals Agency (ECHA) unveiled an updated proposal under REACH to restrict PFAS broadly. This marks a key milestone in the universal PFAS restriction process initially submitted by multiple EU countries. The update indicates the regulatory machinery is advancing toward comprehensive PFAS control. <a href=\"https:\/\/echa.europa.eu\/-\/echa-publishes-updated-pfas-restriction-proposal?utm_source=chatgpt.com\" target=\"_blank\">ECHA<\/a><\/p><p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\"><strong> \u00a0 \u00a02. EU Drafting Blanket PFAS Restrictions (August 2025)<\/strong><\/p><p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\">Europe is poised to impose broad restrictions on PFAS, although some exceptions are reportedly being considered. Environmental advocates, particularly ChemSec, condemn any dilution of these measures and urge for a complete ban to safeguard communities and ecosystems. <a href=\"https:\/\/cen.acs.org\/policy\/chemical-regulation\/Europe-drafts-PFAS-restrictions\/103\/web\/2025\/08?utm_source=chatgpt.com\" target=\"_blank\">Chemical &amp; Engineering News<\/a><\/p><p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\"><strong> \u00a0 \u00a03. Ban on PFAS Pesticide Flufenacet (March 2025)<\/strong><br><\/p><p style=\"text-align: left;\">On 12 March 2025, EU Member States adopted the European Commission\u2019s proposal to ban <em>flufenacet<\/em>, a PFAS pesticide and endocrine disruptor that degrades into <em>trifluoroacetic acid <\/em>(TFA), a highly persistent and mobile contaminant now found in water sources. This decision is seen as an important move to protect human health, especially of pregnant women and newborns, and to safeguard Europe\u2019s water systems. <a href=\"https:\/\/www.pan-europe.info\/press-releases\/2025\/03\/eu-member-states-agree-ban-flufenacet-pan-europe-calls-immediate-action-all?utm_source=chatgpt.com\" target=\"_blank\">PAN Europe<\/a><\/p><p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\"><strong> \u00a0 \u00a04. EU Agreement to Ban PFAS &amp; EDCs in Toys by 2030<\/strong><\/p><p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\">On April 10, 2025, EU institutions reached a compromise to ban PFAS and specific endocrine disruptors (like BPA) in toys by 2030\u2014especially those intended for toddlers (e.g.,teething rings). A broader regulation covering all PFAS-containing items is expected around 2026. <a href=\"https:\/\/entrevue.fr\/en\/jouets-toxiques-lue-acte-linterdiction-des-pfas-et-perturbateurs-endocriniens-dici-2030\/?utm_source=chatgpt.com\" target=\"_blank\">entrevue.fr<\/a><\/p><p style=\"text-align: left;\"><br><\/p><h4 style=\"text-align: left;\">Research &amp; Advocacy Highlights<\/h4><p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\"><strong> \u00a0 5. Scientific Advocacy for Tighter PFAS Regulation<\/strong><\/p><p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\">An open letter\u2014endorsed by the European and global endocrine communities\u2014calls for substantial changes to REACH and a universal PFAS restriction. It highlights PFAS prevalence, persistence, and health threats, advocating urgent regulatory reform. <a href=\"https:\/\/www.endocrine.org\/-\/media\/endocrine\/files\/advocacy\/society-letters\/2025\/july\/open-letter-calling-on-the-eu-member-states-to-act-on-endocrine-disrupting-chemicals.pdf?utm_source=chatgpt.com\" target=\"_blank\">Endocrine+1<\/a><a href=\"https:\/\/www.eurospe.org\/espe-joins-the-european-society-of-endocrinology-and-the-endocrine-society-in-a-coordinated-call-on-the-eu-27-member-states-to-step-up-their-ambition-in-tackling-pfas-and-other-endocrine-disrupting-ch\/?utm_source=chatgpt.com\" target=\"_blank\">eurospe.org<\/a><\/p><p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\"><strong> \u00a0 6. Meta-Analysis Emphasizing EDC Risks in Europe<\/strong><\/p><p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\">A systematic review published recently underscores that ED chemical exposure remains a significant and under-recognized public health concern in Europe, calling for reinforced regulations, surveillance, and ongoing research. <a href=\"https:\/\/journal.medtigo.com\/endocrine-disrupting-chemicals-and-health-in-europe-a-systematic-review-and-meta-analysis\/?utm_source=chatgpt.com\" target=\"_blank\">journal.medtigo.com<\/a><\/p><p style=\"text-align: left;\" class=\"last-child\"><br><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td style=\"background-color:transparent;padding-top:20px;padding-bottom:20px;padding-right:24px;padding-left:24px;border:0;border-radius:0\" valign=\"top\" class=\"mceDividerBlockContainer\" id=\"b36\"><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"background-color:transparent;width:100%\" role=\"presentation\" class=\"mceDividerContainer\" data-block-id=\"36\"><tbody><tr><td style=\"min-width:100%;border-top-width:2px;border-top-style:dotted;border-top-color:#d3e2ff;line-height:0;font-size:0\" valign=\"top\" class=\"mceDividerBlock\">\u00a0<\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0\" valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-7\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" id=\"b7\"><table width=\"100%\" style=\"border:0;background-color:transparent;border-radius:0;border-collapse:separate\"><tbody><tr><td style=\"padding-left:48px;padding-right:48px;padding-top:0;padding-bottom:24px\" class=\"mceTextBlockContainer\"><div data-block-id=\"7\" class=\"mceText\" id=\"d7\" style=\"width:100%\"><h1 style=\"text-align: justify;\">Past &amp; Upcoming Event<\/h1><h1 style=\"text-align: justify;\"><\/h1><h4>EUROTOX Congress<\/h4><p class=\"MsoNormal\" style=\"text-align: left;\"><br><\/p><p class=\"MsoNormal last-child\" style=\"text-align: left;\">The 59th Congress of the European Societies of Toxicology, took place <strong>14\u201317 September <\/strong>2025 at the Megaron Athens International Conference Centre, Athens, Greece.<br><br>We joined <strong>experts and stakeholders from across Europe to advance the discussion on how toxicology could better address real-life risks and support sustainable health and well-being. <\/strong>This was also a great opportunity to connect with laboratories that we collaborate with and stakeholders that wanted to learn more about our work.<br><br>As a public-private platform dedicated to the validation of methods for endocrine disruptor detection, Pepper have developed a comprehensive program of organizing, funding, and managing method validation studies. We highlighted how this model accelerate the transition from research to regulatory acceptance, making validated methods available for decision-making sooner. Discussions were held with several interested parties for which method validation is on the horizon or a part of their current program.<br><br><strong>Pepper\u2019s presence at #EUROTOX2025 was an opportunity to share our vision, exchange knowledge, and strengthen collaborations toward safer and healthier societies.<br><br>Notably, we presented a poster on the validation study of a RAR transactivation method <\/strong>(poster no. P18-64 in topic T-18 <em>In silico<\/em> and <em>in vitro<\/em> methods, Abstract no. 838).<\/p><\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td style=\"background-color:transparent;padding-top:12px;padding-bottom:12px;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" class=\"mceImageBlockContainer\" align=\"center\" id=\"b110\"><div><!--[if !mso]><!--><\/div><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate;margin:0;vertical-align:top;max-width:100%;width:100%;height:auto\" role=\"presentation\" data-testid=\"image-110\"><tbody><tr><td style=\"border:0;border-radius:0;margin:0\" valign=\"top\"><img decoding=\"async\" alt=\"\" src=\"https:\/\/mcusercontent.com\/679c707fab1e7bd2bc8364edc\/images\/07868ef7-22c0-95b3-fab4-dc778d5a39cf.jpg\" width=\"660\" height=\"auto\" style=\"display:block;max-width:100%;height:auto;border-radius:0\" class=\"imageDropZone mceImage\" data-block-id=\"110\"><\/td><\/tr><\/tbody><\/table><div><!--<![endif]--><\/div><div>\n<!--[if mso]>\n<span class=\"mceImageBorder\" style=\"border:0;border-width:2px;vertical-align:top;margin:0\"><img decoding=\"async\" role=\"presentation\" class=\"imageDropZone mceImage\" src=\"https:\/\/mcusercontent.com\/679c707fab1e7bd2bc8364edc\/images\/07868ef7-22c0-95b3-fab4-dc778d5a39cf.jpg\" alt=\"\" width=\"660\" height=\"auto\" style=\"display:block;max-width:660px;width:660px;height:auto\"\/><\/span>\n<![endif]-->\n<\/div><\/td><\/tr><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0\" valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-97\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" id=\"b97\"><table width=\"100%\" style=\"border:0;background-color:transparent;border-radius:0;border-collapse:separate\"><tbody><tr><td style=\"padding-left:24px;padding-right:24px;padding-top:12px;padding-bottom:12px\" class=\"mceTextBlockContainer\"><div data-block-id=\"97\" class=\"mceText\" id=\"d97\" style=\"width:100%\"><p><br><\/p><h4>Pepper at the 16th International Akademie Fresenius Conference on Endocrine Disruptors <\/h4><h4><\/h4><p>\ud83d\udcc5 \u00a0 25\u201326 November 2025 <\/p><p>\ud83d\udccd \u00a0 D\u00fcsseldorf, Germany \/ Live Stream<br><br>Pepper is pleased to announce that Torben will be representing us at the 16th International Akademie Fresenius Conference on Endocrine Disruptors, scheduled for 25\u201326 November 2025 in D\u00fcsseldorf, Germany\u2014or you can<strong> catch his presentation via live stream<\/strong><a href=\"https:\/\/www.akademie-fresenius.com\/events\/detail\/16th-international-akademie-fresenius-conference-endocrine-disruptors-134075?utm_source=chatgpt.com\" target=\"_blank\"> akademie-fresenius.com<\/a><br><br>Torben will deliver an oral presentation titled:<br><em>\u201cThe Pepper experiences with ring-trial validation of methods in the ED space\u201d<\/em><br><br>In his talk, he will cover:<\/p><ul><li><p>Requirements and readiness of endocrine disruptor (ED) test methods<\/p><\/li><li><p>Organizing validation projects<\/p><\/li><li><p>Submission and review under the OECD Test Guidelines (TG) system<br><\/p><\/li><\/ul><p class=\"last-child\"><strong>This presentation underscores Pepper\u2019s hands-on expertise in structuring and managing method validation studies to meet regulatory readiness.<\/strong> Attendees will gain insight into the full validation lifecycle\u2014from method assessment to regulatory submission.<br><br>\u00a0<span style=\"color:#ffffff;\"><span style=\"background-color: #1d417d\"> \u00a0 10 % early bird discount offer &#8211; valid until 30 September 2025 | Code: ENDOCRINE10<\/span><\/span><span style=\"color:#d3e2ff;\"><span style=\"background-color: #1d417d\"> \u00a0<\/span><\/span><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td style=\"background-color:transparent;padding-top:12px;padding-bottom:12px;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" class=\"mceImageBlockContainer\" align=\"center\" id=\"b98\"><div><!--[if !mso]><!--><\/div><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"61%\" style=\"border-collapse:separate;margin:0;vertical-align:top;max-width:61%;width:61%;height:auto\" role=\"presentation\" data-testid=\"image-98\"><tbody><tr><td style=\"border:0;border-radius:0;margin:0\" valign=\"top\"><img decoding=\"async\" alt=\"\" src=\"https:\/\/mcusercontent.com\/679c707fab1e7bd2bc8364edc\/images\/3307b872-9d73-7d1b-711d-f343421eca5a.png\" width=\"402.59999999999997\" height=\"auto\" style=\"display:block;max-width:100%;height:auto;border-radius:0\" class=\"imageDropZone mceImage\" data-block-id=\"98\"><\/td><\/tr><\/tbody><\/table><div><!--<![endif]--><\/div><div>\n<!--[if mso]>\n<span class=\"mceImageBorder\" style=\"border:0;border-width:2px;vertical-align:top;margin:0\"><img decoding=\"async\" role=\"presentation\" class=\"imageDropZone mceImage\" src=\"https:\/\/mcusercontent.com\/679c707fab1e7bd2bc8364edc\/images\/3307b872-9d73-7d1b-711d-f343421eca5a.png\" alt=\"\" width=\"402.59999999999997\" height=\"auto\" style=\"display:block;max-width:402.59999999999997px;width:402.59999999999997px;height:auto\"\/><\/span>\n<![endif]-->\n<\/div><\/td><\/tr><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0\" valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-99\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" id=\"b99\"><table width=\"100%\" style=\"border:0;background-color:transparent;border-radius:0;border-collapse:separate\"><tbody><tr><td style=\"padding-left:24px;padding-right:24px;padding-top:12px;padding-bottom:12px\" class=\"mceTextBlockContainer\"><div data-block-id=\"99\" class=\"mceText\" id=\"d99\" style=\"width:100%\"><p style=\"text-align: left;\" class=\"last-child\"> \u00a0 \u00a0 \u27a1\ufe0f<span style=\"font-family: 'DM Sans', sans-serif\"> <\/span><a href=\"https:\/\/www.akademie-fresenius.com\/endocrine\" target=\"_blank\"><span style=\"font-family: 'DM Sans', sans-serif\">Information <\/span><\/a><span style=\"font-family: 'DM Sans', sans-serif\"><br><\/span> \u00a0 \u00a0 \u27a1\ufe0f <a href=\"https:\/\/www.linkedin.com\/posts\/akademie-fresenius_programme-endocrine-disruptors-activity-7370727727105994752-q23s?utm_source=share&#038;utm_medium=member_desktop&#038;rcm=ACoAAAjJ6f0BpksHTmopzoW94cNAC5UtxoUiL8g\" target=\"_blank\"><span style=\"font-family: 'DM Sans', sans-serif\">Full program<\/span><\/a><span style=\"font-family: 'DM Sans', sans-serif\"> <\/span><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td style=\"background-color:transparent;padding-top:20px;padding-bottom:20px;padding-right:24px;padding-left:24px;border:0;border-radius:0\" valign=\"top\" class=\"mceDividerBlockContainer\" id=\"b50\"><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"background-color:transparent;width:100%\" role=\"presentation\" class=\"mceDividerContainer\" data-block-id=\"50\"><tbody><tr><td style=\"min-width:100%;border-top-width:2px;border-top-style:dotted;border-top-color:#d3e2ff;line-height:0;font-size:0\" valign=\"top\" class=\"mceDividerBlock\">\u00a0<\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0\" valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-111\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" id=\"b111\"><table width=\"100%\" style=\"border:0;background-color:transparent;border-radius:0;border-collapse:separate\"><tbody><tr><td style=\"padding-left:24px;padding-right:24px;padding-top:12px;padding-bottom:12px\" class=\"mceTextBlockContainer\"><div data-block-id=\"111\" class=\"mceText\" id=\"d111\" style=\"width:100%\"><p><br><\/p><h1 class=\"mcePastedContent last-child\">Pepper\u2019s News<\/h1><\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td style=\"background-color:transparent;padding-top:12px;padding-bottom:12px;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" class=\"mceImageBlockContainer\" align=\"center\" id=\"b112\"><div><!--[if !mso]><!--><\/div><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"37%\" style=\"border-collapse:separate;margin:0;vertical-align:top;max-width:37%;width:37%;height:auto\" role=\"presentation\" data-testid=\"image-112\"><tbody><tr><td style=\"border:0;border-radius:0;margin:0\" valign=\"top\"><img decoding=\"async\" alt=\"\" src=\"https:\/\/mcusercontent.com\/679c707fab1e7bd2bc8364edc\/images\/0d2e332a-82c3-7232-29ca-e669dc246d44.jpg\" width=\"244.2\" height=\"auto\" style=\"display:block;max-width:100%;height:auto;border-radius:0\" class=\"imageDropZone mceImage\" data-block-id=\"112\"><\/td><\/tr><\/tbody><\/table><div><!--<![endif]--><\/div><div>\n<!--[if mso]>\n<span class=\"mceImageBorder\" style=\"border:0;border-width:2px;vertical-align:top;margin:0\"><img decoding=\"async\" role=\"presentation\" class=\"imageDropZone mceImage\" src=\"https:\/\/mcusercontent.com\/679c707fab1e7bd2bc8364edc\/images\/0d2e332a-82c3-7232-29ca-e669dc246d44.jpg\" alt=\"\" width=\"244.2\" height=\"auto\" style=\"display:block;max-width:244.2px;width:244.2px;height:auto\"\/><\/span>\n<![endif]-->\n<\/div><\/td><\/tr><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0\" valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-34\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" id=\"b34\"><table width=\"100%\" style=\"border:0;background-color:transparent;border-radius:0;border-collapse:separate\"><tbody><tr><td style=\"padding-left:48px;padding-right:48px;padding-top:10px;padding-bottom:24px\" class=\"mceTextBlockContainer\"><div data-block-id=\"34\" class=\"mceText\" id=\"d34\" style=\"width:100%\"><h4>New validation report<\/h4><p class=\"MsoNormal\" style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\"><span style=\"color:rgb(34, 34, 34);\"><span style=\"font-family: 'DM Sans', sans-serif\"><span style=\"background-color: rgb(255, 255, 255)\">This summer Pepper submitted its <\/span><\/span><\/span><strong><span style=\"color:rgb(34, 34, 34);\"><span style=\"font-family: 'DM Sans', sans-serif\"><span style=\"background-color: rgb(255, 255, 255)\">second Validation Report to OECD following the finalization of a successful validation project.<\/span><\/span><\/span><\/strong><span style=\"color:rgb(34, 34, 34);\"><span style=\"font-family: 'DM Sans', sans-serif\"><span style=\"background-color: rgb(255, 255, 255)\"> This time the project was for a retinoic acid receptor transactivation assay (RARTA) covering a key biological system in endocrine disruption. The project involved four laboratories that tested 30 blinded chemicals with great concordance and reproducibility. The project report is now under peer review that will end in Q1 of 2026 after which we aim to continue toward an OECD test guideline drafting.<\/span><\/span><\/span><\/p><p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\"><br><\/p><h4 style=\"text-align: left;\">Pepper\u2019s Publication<br><\/h4><p style=\"text-align: left;\" class=\"last-child\">Peppers first article on a method validation study was published over the summer in Toxicology In Vitro: \u00a0\u201cInter-laboratory validation study of an in vitro glucocorticoid receptor transactivation assay for testing potential endocrine disrupting chemicals\u201d. The article highlight the successful ring-trial validation from the first generation of validation projects at Pepper.<br>The article covers a multi-laboratory validation study of a Glucocorticoid receptor transactivation assay. Thanks to all involved laboratories, data manager and statistician, and to our sponsors in achieving this milestone.<br><br> \u00a0 \u00a0 \u27a1\ufe0f <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0887233325001031?via%3Dihub\" target=\"_blank\">Read the article online<\/a><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-101\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:12px;padding-bottom:12px;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" class=\"mceLayoutContainer\" id=\"b101\"><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\" data-block-id=\"101\" id=\"section_6553efa6b080e413841fba5fcd7c32b2\" class=\"mceLayout\"><tbody><tr class=\"mceRow\"><td style=\"background-position:center;background-repeat:no-repeat;background-size:cover\" valign=\"top\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td valign=\"top\" class=\"mceColumn\" id=\"mceColumnId--22\" data-block-id=\"-22\" colspan=\"12\" width=\"100%\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"border:0;border-radius:0\" valign=\"top\" align=\"center\" id=\"b-12\"><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\" data-block-id=\"-12\"><tbody><tr class=\"mceRow\"><td style=\"background-position:center;background-repeat:no-repeat;background-size:cover\" valign=\"top\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td valign=\"top\" class=\"mceColumn\" id=\"mceColumnId--27\" data-block-id=\"-27\" colspan=\"12\" width=\"100%\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"border:0;border-radius:0\" valign=\"top\" id=\"b106\"><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\" data-block-id=\"106\"><tbody><tr class=\"mceRow\"><td style=\"background-position:center;background-repeat:no-repeat;background-size:cover;padding-top:0px;padding-bottom:0px\" valign=\"top\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"24\" width=\"100%\" style=\"table-layout:fixed\" role=\"presentation\"><colgroup><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><\/colgroup><tbody><tr><td style=\"padding-top:0;padding-bottom:0\" valign=\"top\" class=\"mceColumn\" id=\"mceColumnId-103\" data-block-id=\"103\" colspan=\"4\" width=\"33.33333333333333%\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"background-color:transparent;padding-top:12px;padding-bottom:12px;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" class=\"mceImageBlockContainer\" align=\"center\" id=\"b107\"><div><!--[if !mso]><!--><\/div><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"85%\" style=\"border-collapse:separate;margin:0;vertical-align:top;max-width:85%;width:85%;height:auto\" role=\"presentation\" data-testid=\"image-107\"><tbody><tr><td style=\"border:0;border-radius:0;margin:0\" valign=\"top\"><img decoding=\"async\" alt=\"\" src=\"https:\/\/mcusercontent.com\/679c707fab1e7bd2bc8364edc\/images\/d1189c41-b8b2-cce9-038d-fcf27d3748bf.png\" width=\"187\" height=\"auto\" style=\"display:block;max-width:100%;height:auto;border-radius:0\" class=\"imageDropZone mceImage\" data-block-id=\"107\"><\/td><\/tr><\/tbody><\/table><div><!--<![endif]--><\/div><div>\n<!--[if mso]>\n<span class=\"mceImageBorder\" style=\"border:0;border-width:2px;vertical-align:top;margin:0\"><img decoding=\"async\" role=\"presentation\" class=\"imageDropZone mceImage\" src=\"https:\/\/mcusercontent.com\/679c707fab1e7bd2bc8364edc\/images\/d1189c41-b8b2-cce9-038d-fcf27d3748bf.png\" alt=\"\" width=\"187\" height=\"auto\" style=\"display:block;max-width:187px;width:187px;height:auto\"\/><\/span>\n<![endif]-->\n<\/div><\/td><\/tr><\/tbody><\/table><\/td><td style=\"padding-top:0;padding-bottom:0\" valign=\"top\" class=\"mceColumn\" id=\"mceColumnId-105\" data-block-id=\"105\" colspan=\"8\" width=\"66.66666666666666%\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0\" valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-108\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" id=\"b108\"><table width=\"100%\" style=\"border:0;background-color:transparent;border-radius:0;border-collapse:separate\"><tbody><tr><td style=\"padding-left:24px;padding-right:24px;padding-top:12px;padding-bottom:12px\" class=\"mceTextBlockContainer\"><div data-block-id=\"108\" class=\"mceText\" id=\"d108\" style=\"width:100%\"><p style=\"text-align: left;\" class=\"last-child\"><em><span style=\"color:rgb(33, 33, 33);\"><span style=\"font-size: 12px\"><span style=\"font-family: Aptos, sans-serif\">A validation study with four laboratories was performed on a glucocorticoid receptor transactivation method. The laboratories setup the method based on instructions from the developing laboratory from INSERM. Then a blinded ring-trial was performed on 34 chemicals with very high concordance between and responsibility within the laboratories. Also, the concordance with expected results on the chemicals was strong. Thus, the method is now under consideration for acceptance as test guideline under OECD.<\/span><\/span><\/span><\/em><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0\" valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-100\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" id=\"b100\"><table width=\"100%\" style=\"border:0;background-color:transparent;border-radius:0;border-collapse:separate\"><tbody><tr><td style=\"padding-left:48px;padding-right:48px;padding-top:10px;padding-bottom:24px\" class=\"mceTextBlockContainer\"><div data-block-id=\"100\" class=\"mceText\" id=\"d100\" style=\"width:100%\"><p><br><\/p><h4>Pepper\u2019s first draft test guideline submission <br><\/h4><p style=\"text-align: left;\">Last year Pepper submitted the first Validation report to OECD for the glucocorticoid receptor transactivation assay (see article section). The report has since undergone peer review which led to updating of the report, answering of the raised questions and suggestions and to the drafting of a test guideline based the method procedure. These documents were submitted to OECD and will be the subject of further scrutiny by their expert group with the aim to have the draft test guideline adopted into the OECD test guideline system. <strong>The first meeting on the draft guideline is to be held in October and Pepper is looking forward to this interaction to help improve the draft guideline and to gain experience with this part of the OECD process.<\/strong> Pepper has this year submitted a second Validation report for review (see New Validation report section) and will regularly do so as more validation projects are finalized in the coming years.<\/p><p style=\"text-align: left;\" class=\"last-child\"><br><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-114\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:12px;padding-bottom:12px;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" class=\"mceLayoutContainer\" id=\"b114\"><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\" data-block-id=\"114\" id=\"section_f12da2be3dfa8f67735889b89028550a\" class=\"mceLayout\"><tbody><tr class=\"mceRow\"><td style=\"background-position:center;background-repeat:no-repeat;background-size:cover\" valign=\"top\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td valign=\"top\" class=\"mceColumn\" id=\"mceColumnId--23\" data-block-id=\"-23\" colspan=\"12\" width=\"100%\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"border:0;border-radius:0\" valign=\"top\" align=\"center\" id=\"b-14\"><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\" data-block-id=\"-14\"><tbody><tr class=\"mceRow\"><td style=\"background-position:center;background-repeat:no-repeat;background-size:cover\" valign=\"top\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td valign=\"top\" class=\"mceColumn\" id=\"mceColumnId--28\" data-block-id=\"-28\" colspan=\"12\" width=\"100%\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"border:0;border-radius:0\" valign=\"top\" id=\"b119\"><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\" data-block-id=\"119\"><tbody><tr class=\"mceRow\"><td style=\"background-position:center;background-repeat:no-repeat;background-size:cover;padding-top:0px;padding-bottom:0px\" valign=\"top\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"24\" width=\"100%\" style=\"table-layout:fixed\" role=\"presentation\"><colgroup><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><col span=\"1\" width=\"8.333333333333332%\"><\/colgroup><tbody><tr><td style=\"padding-top:0;padding-bottom:0\" valign=\"top\" class=\"mceColumn\" id=\"mceColumnId-116\" data-block-id=\"116\" colspan=\"9\" width=\"75%\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0\" valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-113\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" id=\"b113\"><table width=\"100%\" style=\"border:0;background-color:transparent;border-radius:0;border-collapse:separate\"><tbody><tr><td style=\"padding-left:48px;padding-right:48px;padding-top:10px;padding-bottom:24px\" class=\"mceTextBlockContainer\"><div data-block-id=\"113\" class=\"mceText\" id=\"d113\" style=\"width:100%\"><p><br><\/p><h4>Pepper Prepares for Public Utility Recognition: Member Recruitment Campaign Ahead<\/h4><p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\"><span style=\"color:rgb(33, 33, 33);\"><span style=\"font-family: 'DM Sans', sans-serif\">After five successful years advancing non-animal methods (NAMs) validation in endocrine disruption testing, Pepper is ready for a new challenge<\/span><\/span><strong><span style=\"color:rgb(33, 33, 33);\"><span style=\"font-family: 'DM Sans', sans-serif\">: achieving official &#8220;public utility&#8221; recognition from the French state<\/span><\/span><\/strong><span style=\"color:rgb(33, 33, 33);\"><span style=\"font-family: 'DM Sans', sans-serif\">.<\/span><\/span><\/p><p style=\"text-align: left;\"><span style=\"color:rgb(33, 33, 33);\"><span style=\"font-family: 'DM Sans', sans-serif\">To support this milestone, we will soon launch a member recruitment campaign. With 13 methods at various validation stages and our first success stories now emerging,\u00a0<\/span><\/span><strong><span style=\"color:rgb(33, 33, 33);\"><span style=\"font-family: 'DM Sans', sans-serif\">Pepper has demonstrated the maturity needed for this recognition.<\/span><\/span><\/strong><\/p><p style=\"text-align: left;\"><span style=\"color:rgb(33, 33, 33);\"><span style=\"font-family: 'DM Sans', sans-serif\">This status would formalize\u00a0<\/span><\/span><strong><span style=\"color:rgb(33, 33, 33);\"><span style=\"font-family: 'DM Sans', sans-serif\">our unique role in bridging the gap between NAM research and regulatory approval<\/span><\/span><\/strong><span style=\"color:rgb(33, 33, 33);\"><span style=\"font-family: 'DM Sans', sans-serif\">, reinforcing our commitment to reducing animal testing while protecting public health.<\/span><\/span><\/p><p style=\"text-align: left;\" class=\"last-child\"><strong><span style=\"color:rgb(33, 33, 33);\"><span style=\"font-family: 'DM Sans', sans-serif\">Stay tuned<\/span><\/span><\/strong><span style=\"color:rgb(33, 33, 33);\"><span style=\"font-family: 'DM Sans', sans-serif\">\u00a0for details on joining this exciting next chapter in Pepper&#8217;s development.<\/span><\/span><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><td style=\"padding-top:0;padding-bottom:0\" valign=\"top\" class=\"mceColumn\" id=\"mceColumnId-118\" data-block-id=\"118\" colspan=\"3\" width=\"25%\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\"><tbody><tr><td style=\"background-color:transparent;border:0;border-radius:0\" valign=\"top\" id=\"b121\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" role=\"presentation\" data-block-id=\"121\"><tbody><tr><td valign=\"top\" class=\"mceSpacerBlock\" height=\"82\"><\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td style=\"background-color:transparent;padding-top:12px;padding-bottom:12px;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" class=\"mceImageBlockContainer\" align=\"center\" id=\"b120\"><div><!--[if !mso]><!--><\/div><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"85%\" style=\"border-collapse:separate;margin:0;vertical-align:top;max-width:85%;width:85%;height:auto\" role=\"presentation\" data-testid=\"image-120\"><tbody><tr><td style=\"border:0;border-radius:0;margin:0\" valign=\"top\"><img decoding=\"async\" alt=\"\" src=\"https:\/\/mcusercontent.com\/679c707fab1e7bd2bc8364edc\/images\/cb23efef-80a6-6770-c827-a90f2b6302f7.jpg\" width=\"140.25\" height=\"auto\" style=\"display:block;max-width:100%;height:auto;border-radius:0\" class=\"imageDropZone mceImage\" data-block-id=\"120\"><\/td><\/tr><\/tbody><\/table><div><!--<![endif]--><\/div><div>\n<!--[if mso]>\n<span class=\"mceImageBorder\" style=\"border:0;border-width:2px;vertical-align:top;margin:0\"><img decoding=\"async\" role=\"presentation\" class=\"imageDropZone mceImage\" src=\"https:\/\/mcusercontent.com\/679c707fab1e7bd2bc8364edc\/images\/cb23efef-80a6-6770-c827-a90f2b6302f7.jpg\" alt=\"\" width=\"140.25\" height=\"auto\" style=\"display:block;max-width:140.25px;width:140.25px;height:auto\"\/><\/span>\n<![endif]-->\n<\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td style=\"background-color:transparent;padding-top:20px;padding-bottom:20px;padding-right:24px;padding-left:24px;border:0;border-radius:0\" valign=\"top\" class=\"mceDividerBlockContainer\" id=\"b53\"><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"background-color:transparent;width:100%\" role=\"presentation\" class=\"mceDividerContainer\" data-block-id=\"53\"><tbody><tr><td style=\"min-width:100%;border-top-width:2px;border-top-style:dotted;border-top-color:#d3e2ff;line-height:0;font-size:0\" valign=\"top\" class=\"mceDividerBlock\">\u00a0<\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0\" valign=\"top\" class=\"mceGutterContainer\" id=\"gutterContainerId-29\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\" style=\"border-collapse:separate\" role=\"presentation\"><tbody><tr><td style=\"padding-top:0;padding-bottom:0;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" id=\"b29\"><table width=\"100%\" style=\"border:0;background-color:transparent;border-radius:0;border-collapse:separate\"><tbody><tr><td style=\"padding-left:48px;padding-right:48px;padding-top:10px;padding-bottom:5px\" class=\"mceTextBlockContainer\"><div data-block-id=\"29\" class=\"mceText\" id=\"d29\" style=\"width:100%\"><h1 style=\"text-align: justify;\"><strong>NAMWISE updates<\/strong><\/h1><p style=\"text-align: justify;\"><br><\/p><p style=\"text-align: left;\"><span style=\"font-family: 'DM Sans', sans-serif\">\ud835\udde7\ud835\uddf5\ud835\uddf2 \ud835\udde1\ud835\uddd4\ud835\udde0\ud835\uddea\ud835\udddc\ud835\udde6\ud835\uddd8 \ud835\udde3\ud835\uddff\ud835\uddfc\ud835\uddf7\ud835\uddf2\ud835\uddf0\ud835\ude01 \ud835\uddf6\ud835\ude00 \ud835\uddfc\ud835\uddfb \ud835\uddec\ud835\uddfc\ud835\ude02\ud835\udde7\ud835\ude02\ud835\uddef\ud835\uddf2!<br>NAMWISE YouTube channel is your go-to space for insights into the future of New Approach Methodologies (NAMs).<br><br>You can already find there \ud835\uddf2\ud835\ude05\ud835\uddf0\ud835\uddf9\ud835\ude02\ud835\ude00\ud835\uddf6\ud835\ude03\ud835\uddf2 \ud835\uddf6\ud835\uddfb\ud835\ude01\ud835\uddf2\ud835\uddff\ud835\ude03\ud835\uddf6\ud835\uddf2\ud835\ude04\ud835\ude00 with the project coordinator Laure Geoffroy (INERIS), diving into the vision, goals, and progress of NAMWISE.<\/span><\/p><p><span style=\"font-family: 'DM Sans', sans-serif\">\u27a1\ufe0f \u00a0<\/span><a href=\"https:\/\/www.youtube.com\/@NAMWISE_EU\" target=\"_blank\">Watch the interviews<\/a><span style=\"font-family: 'DM Sans', sans-serif\"><br><br>The \ud835\udde1\ud835\uddd4\ud835\udde0\ud835\uddea\ud835\udddc\ud835\udde6\ud835\uddd8 \ud835\uddfd\ud835\uddff\ud835\uddfc\ud835\uddf7\ud835\uddf2\ud835\uddf0\ud835\ude01 aims to \ud835\uddf1\ud835\uddff\ud835\uddf6\ud835\ude03\ud835\uddf2 \ud835\ude01\ud835\uddf5\ud835\uddf2 \ud835\uddee\ud835\uddf1\ud835\uddfc\ud835\uddfd\ud835\ude01\ud835\uddf6\ud835\uddfc\ud835\uddfb \ud835\uddee\ud835\uddfb\ud835\uddf1 \ud835\uddf6\ud835\uddfb\ud835\ude01\ud835\uddf2\ud835\uddf4\ud835\uddff\ud835\uddee\ud835\ude01\ud835\uddf6\ud835\uddfc\ud835\uddfb \ud835\uddfc\ud835\uddf3 \ud835\udde1\ud835\uddd4\ud835\udde0\ud835\ude00 for assessing the \ud835\ude00\ud835\uddee\ud835\uddf3\ud835\uddf2\ud835\ude01\ud835\ude06 \ud835\uddee\ud835\uddfb\ud835\uddf1 \ud835\uddf2\ud835\uddf3\ud835\uddf3\ud835\uddf6\ud835\uddf0\ud835\uddee\ud835\uddf0\ud835\ude06 \ud835\uddfc\ud835\uddf3 \ud835\uddf0\ud835\uddf5\ud835\uddf2\ud835\uddfa\ud835\uddf6\ud835\uddf0\ud835\uddee\ud835\uddf9\ud835\ude00 \ud835\uddee\ud835\uddfb\ud835\uddf1 \ud835\uddfd\ud835\uddf5\ud835\uddee\ud835\uddff\ud835\uddfa\ud835\uddee\ud835\uddf0\ud835\uddf2\ud835\ude02\ud835\ude01\ud835\uddf6\ud835\uddf0\ud835\uddee\ud835\uddf9\ud835\ude00. By delivering recommendations, guidance, and training resources, NAMWISE is paving the way toward effective validation and implementation of NAMs.<br><br> Stay connected with NAMWISE! <\/span><\/p><p class=\"last-child\"><span style=\"font-family: &quot;DM Sans&quot;, sans-serif\">\u27a1\ufe0f \u00a0<\/span><a href=\"https:\/\/lv57.mj.am\/wgt\/lv57\/00s8\/form?c=d642a225\" target=\"_blank\"><span style=\"font-family: 'DM Sans', sans-serif\">Subscribe to the newsletter<br><\/span><\/a><br><\/p><\/div><\/td><\/tr><\/tbody><\/table><\/td><\/tr><\/tbody><\/table><\/td><\/tr><tr><td style=\"background-color:transparent;padding-top:12px;padding-bottom:12px;padding-right:0;padding-left:0;border:0;border-radius:0\" valign=\"top\" class=\"mceImageBlockContainer\" align=\"center\" id=\"b109\"><div><!--[if !mso]><!--><\/div><table align=\"center\" border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"63%\" 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Dive into the latest on endocrine disruption, regulation, method validation, and Pepper\u2019s journey bridging research and regulatory impact. \ud83d\udd0d What\u2019s inside this issue: \ud83d\udea8 Policy spotlights\ud83d\udcc5 Events recap &amp; upcoming\ud83e\uddea Pepper news: New validation report submitted to OECD, draft test guideline progress, &#8230;\ud83d\udce3 NAMWISE update: New [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":7981,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[52,51],"tags":[],"class_list":["post-7977","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-newsletter","category-pepper-en"],"_links":{"self":[{"href":"https:\/\/ed-pepper.eu\/en\/wp-json\/wp\/v2\/posts\/7977","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ed-pepper.eu\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ed-pepper.eu\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ed-pepper.eu\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/ed-pepper.eu\/en\/wp-json\/wp\/v2\/comments?post=7977"}],"version-history":[{"count":2,"href":"https:\/\/ed-pepper.eu\/en\/wp-json\/wp\/v2\/posts\/7977\/revisions"}],"predecessor-version":[{"id":7980,"href":"https:\/\/ed-pepper.eu\/en\/wp-json\/wp\/v2\/posts\/7977\/revisions\/7980"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ed-pepper.eu\/en\/wp-json\/wp\/v2\/media\/7981"}],"wp:attachment":[{"href":"https:\/\/ed-pepper.eu\/en\/wp-json\/wp\/v2\/media?parent=7977"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ed-pepper.eu\/en\/wp-json\/wp\/v2\/categories?post=7977"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ed-pepper.eu\/en\/wp-json\/wp\/v2\/tags?post=7977"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}